| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 03-Sep-05 | at Iowa (21) | 0-56 | Lost | 1.2327 | 0.0000 |
| 10-Sep-05 | vs Bowling Green (85) | 31-40 | Lost | -0.6558 | -1.0000 |
| 17-Sep-05 | at Auburn (11) | 3-63 | Lost | 1.5238 | 0.0000 |
| 01-Oct-05 | at Boston College (23) | 0-38 | Lost | 1.0990 | 0.0000 |
| 08-Oct-05 | at Western Michigan (72) | 60-57 | Won | -0.1228 | 1.0000 |
| 15-Oct-05 | vs Toledo (62) | 14-34 | Lost | -0.1886 | -0.7751 |
| 22-Oct-05 | at Ohio U. (93) | 21-38 | Lost | -0.6740 | -1.0000 |
| 29-Oct-05 | at Northern Illinois (56) | 31-17 | Won | 0.2346 | 1.0000 |
| 05-Nov-05 | vs Akron (78) | 23-17 | Won | -0.5027 | 0.9108 |
| 12-Nov-05 | at Eastern Michigan (97) | 26-25 | Won | -0.8260 | 0.5875 |
| 19-Nov-05 | vs Central Michigan (60) | 24-31 | Lost | -0.1554 | -0.7419 |
A red opponent rating indicates modification according to home field advantage (0.1322).