| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 01-Sep-05 | at Cincinnati (82) | 26-28 | Lost | -0.3172 | -0.3590 |
| 10-Sep-05 | vs Louisiana-Lafayette (101) | 31-10 | Won | -1.2995 | 0.6587 |
| 17-Sep-05 | at Michigan (12) | 0-55 | Lost | 1.5040 | 0.0000 |
| 24-Sep-05 | at Central Michigan (60) | 23-20 | Won | 0.1090 | 1.0000 |
| 01-Oct-05 | vs Kent St (119) | 27-20 | Won | -3.1276 | -0.0000 |
| 08-Oct-05 | at Toledo (62) | 3-30 | Lost | 0.0758 | 0.0000 |
| 15-Oct-05 | at Northern Illinois (56) | 8-24 | Lost | 0.2346 | 0.0000 |
| 22-Oct-05 | vs Miami OH (71) | 23-24 | Lost | -0.3788 | -0.4206 |
| 05-Nov-05 | vs Western Michigan (72) | 36-44 | Lost | -0.3872 | -0.4290 |
| 12-Nov-05 | vs Ball St (80) | 25-26 | Lost | -0.5457 | -0.5875 |
| 19-Nov-05 | at Buffalo (115) | 38-14 | Won | -1.8855 | 0.0728 |
A red opponent rating indicates modification according to home field advantage (0.1322).