| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 03-Sep-05 | at Michigan (12) | 17-33 | Lost | 1.5040 | 0.0000 |
| 10-Sep-05 | at Northwestern (15) | 37-38 | Lost | 1.4361 | 0.0000 |
| 24-Sep-05 | at Akron (78) | 42-48 | Lost | -0.2383 | -1.0000 |
| 05-Oct-05 | vs Miami OH (71) | 38-27 | Won | -0.3788 | 0.5188 |
| 15-Oct-05 | vs Eastern Michigan (97) | 24-8 | Won | -1.0904 | -0.0000 |
| 22-Oct-05 | at Kent St (119) | 34-3 | Won | -2.8632 | -0.0000 |
| 29-Oct-05 | vs Ball St (80) | 17-31 | Lost | -0.5457 | -1.0000 |
| 05-Nov-05 | at Central Michigan (60) | 31-28 | Won | 0.1090 | 1.0000 |
| 16-Nov-05 | at Toledo (62) | 35-17 | Won | 0.0758 | 0.9734 |
| 23-Nov-05 | vs Western Michigan (72) | 42-7 | Won | -0.3872 | 0.5104 |
| 01-Dec-05 | at Akron (78) | 30-31 | Lost | -0.2383 | -1.0000 |
A red opponent rating indicates modification according to home field advantage (0.1322).