| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 03-Sep-05 | at Northwestern (15) | 14-38 | Lost | 1.4361 | 0.0000 |
| 09-Sep-05 | vs Pittsburgh (63) | 16-10 | Won | -0.1944 | 1.0000 |
| 17-Sep-05 | at Virginia Tech (9) | 0-45 | Lost | 1.5655 | 0.0000 |
| 24-Sep-05 | vs Kent St (119) | 35-32 | Won | -3.1276 | -0.0000 |
| 08-Oct-05 | at Bowling Green (85) | 14-38 | Lost | -0.3913 | -0.5851 |
| 15-Oct-05 | at Central Michigan (60) | 10-37 | Lost | 0.1090 | -0.0848 |
| 22-Oct-05 | vs Ball St (80) | 38-21 | Won | -0.5457 | 1.0000 |
| 29-Oct-05 | at Buffalo (115) | 34-20 | Won | -1.8855 | -0.0000 |
| 04-Nov-05 | vs Toledo (62) | 21-30 | Lost | -0.1886 | -0.3824 |
| 15-Nov-05 | at Akron (78) | 3-27 | Lost | -0.2383 | -0.4321 |
| 21-Nov-05 | vs Miami OH (71) | 7-38 | Lost | -0.3788 | -0.5726 |
A red opponent rating indicates modification according to home field advantage (0.1322).