| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 04-Sep-05 | at North Carolina St (41) | 20-16 | Won | 0.5323 | 0.0990 |
| 10-Sep-05 | at Duke (106) | 45-0 | Won | -1.2233 | -0.0000 |
| 17-Sep-05 | vs Ohio U. (93) | 45-0 | Won | -0.9384 | -0.0000 |
| 24-Sep-05 | vs Georgia Tech (22) | 51-7 | Won | 0.8365 | 0.4033 |
| 01-Oct-05 | at West Virginia (17) | 34-17 | Won | 1.3524 | 0.9192 |
| 08-Oct-05 | vs Marshall (94) | 41-14 | Won | -1.0266 | -0.0000 |
| 20-Oct-05 | at Maryland (42) | 28-9 | Won | 0.5273 | 0.0940 |
| 27-Oct-05 | vs Boston College (23) | 30-10 | Won | 0.8346 | 0.4014 |
| 05-Nov-05 | vs Miami FL (13) | 7-27 | Lost | 1.1858 | -1.0000 |
| 19-Nov-05 | at Virginia (40) | 52-14 | Won | 0.5819 | 0.1487 |
| 26-Nov-05 | vs North Carolina (36) | 30-3 | Won | 0.4630 | 0.0298 |
| 03-Dec-05 | at Florida St (29) | 22-27 | Lost | 0.9323 | -1.0000 |
A red opponent rating indicates modification according to home field advantage (0.1322).