| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Akron (86) | 34-16 | Won | -0.60 | 0.00 |
| 09-Sep-06 | at Notre Dame (16) | 17-41 | Lost | 0.95 | -0.64 |
| 23-Sep-06 | at Ohio State (4) | 6-28 | Lost | 1.34 | -0.25 |
| 30-Sep-06 | vs Northwestern (77) | 33-7 | Won | -0.48 | 0.00 |
| 07-Oct-06 | at Minnesota (50) | 28-27 | Won | 0.34 | 0.75 |
| 14-Oct-06 | vs Michigan (5) | 10-17 | Lost | 0.90 | -0.69 |
| 21-Oct-06 | vs Illinois (108) | 26-12 | Won | -1.02 | 0.00 |
| 28-Oct-06 | at Purdue (49) | 12-0 | Won | 0.36 | 0.77 |
| 04-Nov-06 | at Wisconsin (8) | 3-13 | Lost | 1.23 | -0.36 |
| 11-Nov-06 | vs Temple (111) | 47-0 | Won | -1.09 | 0.00 |
| 18-Nov-06 | vs Michigan St (78) | 17-13 | Won | -0.50 | 0.00 |
| 01-Jan-07 | at Tennessee (21) | 20-10 | Won | 0.69 | 1.00 |
A red opponent rating indicates modification according to home field advantage (0.19).