| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 09-Sep-06 | vs Miami OH (109) | 38-31 | Won | -1.08 | 0.00 |
| 16-Sep-06 | vs Ball St (76) | 38-28 | Won | -0.47 | 0.37 |
| 23-Sep-06 | vs Minnesota (50) | 27-21 | Won | -0.05 | 0.78 |
| 30-Sep-06 | at Notre Dame (16) | 21-35 | Lost | 0.95 | -0.21 |
| 07-Oct-06 | at Iowa (57) | 17-47 | Lost | 0.22 | -0.94 |
| 14-Oct-06 | at Northwestern (77) | 31-10 | Won | -0.09 | 0.75 |
| 21-Oct-06 | vs Wisconsin (8) | 3-24 | Lost | 0.84 | -0.32 |
| 28-Oct-06 | vs Penn State (23) | 0-12 | Lost | 0.39 | -0.77 |
| 04-Nov-06 | at Michigan St (78) | 17-15 | Won | -0.11 | 0.73 |
| 11-Nov-06 | at Illinois (108) | 42-31 | Won | -0.63 | 0.21 |
| 18-Nov-06 | vs Indiana (54) | 28-19 | Won | -0.10 | 0.74 |
| 25-Nov-06 | at Hawai`i (27) | 35-42 | Lost | 0.64 | -0.52 |
| 29-Dec-06 | at Maryland (26) | 7-24 | Lost | 0.49 | -0.67 |
A red opponent rating indicates modification according to home field advantage (0.19).