| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | vs Eastern Michigan (114) | 38-20 | Won | -1.15 | 0.12 |
| 09-Sep-06 | vs Indiana (54) | 23-24 | Lost | -0.10 | -0.82 |
| 16-Sep-06 | at Purdue (49) | 28-38 | Lost | 0.36 | -0.37 |
| 30-Sep-06 | vs Northern Illinois (70) | 28-40 | Lost | -0.38 | -1.00 |
| 07-Oct-06 | at Buffalo (110) | 55-25 | Won | -0.70 | 0.58 |
| 14-Oct-06 | at Central Michigan (38) | 7-18 | Lost | 0.52 | -0.20 |
| 21-Oct-06 | vs Western Michigan (52) | 27-41 | Lost | -0.08 | -0.80 |
| 28-Oct-06 | at Miami OH (109) | 20-17 | Won | -0.69 | 0.58 |
| 04-Nov-06 | at Michigan (5) | 26-34 | Lost | 1.29 | 0.00 |
| 14-Nov-06 | at Toledo (97) | 20-17 | Won | -0.36 | 0.92 |
| 24-Nov-06 | vs Kent St (84) | 30-6 | Won | -0.56 | 0.72 |
A red opponent rating indicates modification according to home field advantage (0.19).