| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | at Iowa St (98) | 43-45 | Lost | -0.39 | -0.84 |
| 09-Sep-06 | at Western Michigan (52) | 10-31 | Lost | 0.31 | -0.14 |
| 15-Sep-06 | vs Kansas (75) | 37-31 | Won | -0.44 | 1.00 |
| 30-Sep-06 | at Pittsburgh (58) | 3-45 | Lost | 0.22 | -0.23 |
| 07-Oct-06 | vs Central Michigan (38) | 20-42 | Lost | 0.13 | -0.31 |
| 14-Oct-06 | at Kent St (84) | 14-40 | Lost | -0.17 | -0.62 |
| 21-Oct-06 | at Eastern Michigan (114) | 13-17 | Lost | -0.76 | -1.00 |
| 28-Oct-06 | vs Akron (86) | 35-20 | Won | -0.60 | 0.95 |
| 07-Nov-06 | at Northern Illinois (70) | 17-13 | Won | 0.01 | 1.00 |
| 14-Nov-06 | vs Ball St (76) | 17-20 | Lost | -0.47 | -0.92 |
| 21-Nov-06 | vs Bowling Green (106) | 31-21 | Won | -0.99 | 0.56 |
A red opponent rating indicates modification according to home field advantage (0.19).