| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Wisconsin (8) | 14-35 | Lost | 1.04 | 0.00 |
| 09-Sep-06 | vs Buffalo (110) | 48-40 | Won | -1.09 | 0.70 |
| 16-Sep-06 | at Florida Int'l (119) | 33-28 | Won | -1.26 | 0.53 |
| 23-Sep-06 | vs Kent St (84) | 3-38 | Lost | -0.56 | -0.77 |
| 30-Sep-06 | at Ohio U. (47) | 21-9 | Won | 0.37 | 1.00 |
| 07-Oct-06 | at Ohio State (4) | 7-35 | Lost | 1.34 | 0.00 |
| 14-Oct-06 | vs Eastern Michigan (114) | 24-21 | Won | -1.15 | 0.64 |
| 19-Oct-06 | at Central Michigan (38) | 14-31 | Lost | 0.52 | 0.00 |
| 28-Oct-06 | at Temple (111) | 14-28 | Lost | -0.70 | -0.91 |
| 04-Nov-06 | at Akron (86) | 28-35 | Lost | -0.21 | -0.42 |
| 15-Nov-06 | vs Miami OH (109) | 7-9 | Lost | -1.08 | -1.00 |
| 21-Nov-06 | at Toledo (97) | 21-31 | Lost | -0.36 | -0.56 |
A red opponent rating indicates modification according to home field advantage (0.19).