| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | vs Temple (111) | 9-3 | Won | -1.09 | 0.80 |
| 09-Sep-06 | at Bowling Green (106) | 40-48 | Lost | -0.60 | -0.70 |
| 16-Sep-06 | at Northern Illinois (70) | 13-31 | Lost | 0.01 | -0.10 |
| 23-Sep-06 | at Auburn (9) | 7-38 | Lost | 1.21 | 0.00 |
| 07-Oct-06 | vs Ball St (76) | 25-55 | Lost | -0.47 | -0.58 |
| 15-Oct-06 | vs Miami OH (109) | 31-38 | Lost | -1.08 | -1.00 |
| 21-Oct-06 | at Ohio U. (47) | 7-42 | Lost | 0.37 | 0.00 |
| 28-Oct-06 | at Boston College (14) | 0-41 | Lost | 1.00 | 0.00 |
| 04-Nov-06 | vs Kent St (84) | 41-14 | Won | -0.56 | 1.00 |
| 09-Nov-06 | at Akron (86) | 16-31 | Lost | -0.21 | -0.32 |
| 18-Nov-06 | at Wisconsin (8) | 3-35 | Lost | 1.23 | 0.00 |
| 24-Nov-06 | vs Central Michigan (38) | 28-55 | Lost | 0.13 | 0.00 |
A red opponent rating indicates modification according to home field advantage (0.19).