| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | at Penn State (23) | 16-34 | Lost | 0.78 | 0.00 |
| 09-Sep-06 | at North Carolina St (102) | 20-17 | Won | -0.50 | 0.90 |
| 16-Sep-06 | at Central Michigan (38) | 21-24 | Lost | 0.52 | -0.07 |
| 23-Sep-06 | vs North Texas (113) | 33-13 | Won | -1.11 | 0.30 |
| 30-Sep-06 | at Kent St (84) | 15-37 | Lost | -0.17 | -0.76 |
| 07-Oct-06 | at Cincinnati (30) | 14-20 | Lost | 0.60 | 0.00 |
| 21-Oct-06 | vs Miami OH (109) | 24-13 | Won | -1.08 | 0.32 |
| 28-Oct-06 | at Toledo (97) | 20-35 | Lost | -0.36 | -0.95 |
| 04-Nov-06 | vs Bowling Green (106) | 35-28 | Won | -0.99 | 0.42 |
| 09-Nov-06 | vs Buffalo (110) | 31-16 | Won | -1.09 | 0.32 |
| 16-Nov-06 | at Ohio U. (47) | 7-17 | Lost | 0.37 | -0.22 |
| 24-Nov-06 | vs Western Michigan (52) | 0-17 | Lost | -0.08 | -0.67 |
A red opponent rating indicates modification according to home field advantage (0.19).