| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | at Indiana (54) | 20-39 | Lost | 0.29 | -0.82 |
| 09-Sep-06 | vs Toledo (97) | 31-10 | Won | -0.75 | 0.14 |
| 16-Sep-06 | at Virginia (72) | 17-10 | Won | -0.02 | 0.86 |
| 23-Sep-06 | vs Temple (111) | 41-7 | Won | -1.09 | 0.00 |
| 07-Oct-06 | at Ohio U. (47) | 20-27 | Lost | 0.37 | -0.75 |
| 14-Oct-06 | vs Northern Illinois (70) | 16-14 | Won | -0.38 | 0.50 |
| 21-Oct-06 | at Ball St (76) | 41-27 | Won | -0.08 | 0.80 |
| 28-Oct-06 | vs Eastern Michigan (114) | 18-15 | Won | -1.15 | 0.00 |
| 04-Nov-06 | vs Miami OH (109) | 27-24 | Won | -1.08 | 0.00 |
| 10-Nov-06 | at Central Michigan (38) | 7-31 | Lost | 0.52 | -0.59 |
| 18-Nov-06 | at Florida St (43) | 20-28 | Lost | 0.42 | -0.70 |
| 24-Nov-06 | at Akron (86) | 17-0 | Won | -0.21 | 0.67 |
A red opponent rating indicates modification according to home field advantage (0.19).