| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | at Ball St (76) | 20-38 | Lost | -0.08 | -0.12 |
| 09-Sep-06 | at Michigan St (78) | 20-52 | Lost | -0.11 | -0.15 |
| 16-Sep-06 | at Northwestern (77) | 6-14 | Lost | -0.09 | -0.13 |
| 23-Sep-06 | vs Central Michigan (38) | 17-24 | Lost | 0.13 | 0.00 |
| 30-Sep-06 | at Louisiana-Lafayette (83) | 14-33 | Lost | -0.15 | -0.20 |
| 14-Oct-06 | at Bowling Green (106) | 21-24 | Lost | -0.60 | -0.64 |
| 21-Oct-06 | vs Toledo (97) | 17-13 | Won | -0.75 | 1.00 |
| 28-Oct-06 | at Western Michigan (52) | 15-18 | Lost | 0.31 | 0.00 |
| 04-Nov-06 | vs Ohio U. (47) | 10-16 | Lost | -0.02 | -0.07 |
| 11-Nov-06 | vs Navy (45) | 21-49 | Lost | 0.19 | 0.00 |
| 17-Nov-06 | at Kent St (84) | 6-14 | Lost | -0.17 | -0.21 |
| 24-Nov-06 | vs Northern Illinois (70) | 0-27 | Lost | -0.38 | -0.43 |
A red opponent rating indicates modification according to home field advantage (0.19).