| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | at Buffalo (110) | 3-9 | Lost | -0.70 | -0.80 |
| 09-Sep-06 | vs Louisville (7) | 0-62 | Lost | 0.87 | 0.00 |
| 16-Sep-06 | at Minnesota (50) | 0-62 | Lost | 0.34 | 0.00 |
| 23-Sep-06 | at Western Michigan (52) | 7-41 | Lost | 0.31 | 0.00 |
| 30-Sep-06 | at Vanderbilt (81) | 14-43 | Lost | -0.14 | -0.25 |
| 07-Oct-06 | vs Kent St (84) | 17-28 | Lost | -0.56 | -0.66 |
| 12-Oct-06 | at Clemson (48) | 9-63 | Lost | 0.17 | 0.00 |
| 21-Oct-06 | at Northern Illinois (70) | 21-43 | Lost | 0.01 | -0.09 |
| 28-Oct-06 | vs Bowling Green (106) | 28-14 | Won | -0.99 | 0.91 |
| 04-Nov-06 | vs Central Michigan (38) | 26-42 | Lost | 0.13 | 0.00 |
| 11-Nov-06 | at Penn State (23) | 0-47 | Lost | 0.78 | 0.00 |
| 18-Nov-06 | at Navy (45) | 6-42 | Lost | 0.39 | 0.00 |
A red opponent rating indicates modification according to home field advantage (0.19).