| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Vanderbilt (81) | 27-7 | Won | -0.53 | 0.00 |
| 09-Sep-06 | vs Central Michigan (38) | 41-17 | Won | 0.13 | 0.04 |
| 16-Sep-06 | at Notre Dame (16) | 47-21 | Won | 0.95 | 0.86 |
| 23-Sep-06 | vs Wisconsin (8) | 27-13 | Won | 0.84 | 0.75 |
| 30-Sep-06 | at Minnesota (50) | 28-14 | Won | 0.34 | 0.24 |
| 07-Oct-06 | vs Michigan St (78) | 31-13 | Won | -0.50 | 0.00 |
| 14-Oct-06 | at Penn State (23) | 17-10 | Won | 0.78 | 0.69 |
| 21-Oct-06 | vs Iowa (57) | 20-6 | Won | -0.17 | 0.00 |
| 28-Oct-06 | vs Northwestern (77) | 17-3 | Won | -0.48 | 0.00 |
| 04-Nov-06 | vs Ball St (76) | 34-26 | Won | -0.47 | 0.00 |
| 11-Nov-06 | at Indiana (54) | 34-3 | Won | 0.29 | 0.20 |
| 18-Nov-06 | at Ohio State (4) | 39-42 | Lost | 1.34 | -0.75 |
| 01-Jan-07 | at Southern Cal (3) | 18-32 | Lost | 1.17 | -0.92 |
A red opponent rating indicates modification according to home field advantage (0.19).