| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | vs Temple (116) | 9-3 | Won | -2.25 | 0.68 |
| 09-Sep-06 | at Bowling Green (113) | 40-48 | Lost | -1.60 | -0.67 |
| 16-Sep-06 | at Northern Illinois (81) | 13-31 | Lost | -0.33 | 0.00 |
| 23-Sep-06 | at Auburn (8) | 7-38 | Lost | 2.39 | 0.00 |
| 07-Oct-06 | vs Ball St (87) | 25-55 | Lost | -1.05 | -0.12 |
| 15-Oct-06 | vs Miami OH (109) | 31-38 | Lost | -1.83 | -0.91 |
| 21-Oct-06 | at Ohio U. (60) | 7-42 | Lost | 0.13 | 0.00 |
| 28-Oct-06 | at Boston College (29) | 0-41 | Lost | 1.19 | 0.00 |
| 04-Nov-06 | vs Kent St (98) | 41-14 | Won | -1.29 | 1.00 |
| 09-Nov-06 | at Akron (102) | 16-31 | Lost | -0.94 | -0.02 |
| 18-Nov-06 | at Wisconsin (6) | 3-35 | Lost | 2.48 | 0.00 |
| 24-Nov-06 | vs Central Michigan (55) | 28-55 | Lost | -0.27 | 0.00 |
A red opponent rating indicates modification according to home field advantage (0.24).