| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | at Penn State (14) | 16-34 | Lost | 1.76 | 0.00 |
| 09-Sep-06 | at North Carolina St (99) | 20-17 | Won | -0.85 | 1.00 |
| 16-Sep-06 | at Central Michigan (55) | 21-24 | Lost | 0.21 | 0.00 |
| 23-Sep-06 | vs North Texas (112) | 33-13 | Won | -2.00 | 0.19 |
| 30-Sep-06 | at Kent St (98) | 15-37 | Lost | -0.81 | -0.62 |
| 07-Oct-06 | at Cincinnati (34) | 14-20 | Lost | 0.82 | 0.00 |
| 21-Oct-06 | vs Miami OH (109) | 24-13 | Won | -1.83 | 0.35 |
| 28-Oct-06 | at Toledo (104) | 20-35 | Lost | -0.99 | -0.81 |
| 04-Nov-06 | vs Bowling Green (113) | 35-28 | Won | -2.08 | 0.10 |
| 09-Nov-06 | vs Buffalo (115) | 31-16 | Won | -2.17 | 0.02 |
| 16-Nov-06 | at Ohio U. (60) | 7-17 | Lost | 0.13 | 0.00 |
| 24-Nov-06 | vs Western Michigan (64) | 0-17 | Lost | -0.44 | -0.25 |
A red opponent rating indicates modification according to home field advantage (0.24).