| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | at Indiana (48) | 20-39 | Lost | 0.36 | -0.44 |
| 09-Sep-06 | vs Toledo (104) | 31-10 | Won | -1.48 | 0.00 |
| 16-Sep-06 | at Virginia (76) | 17-10 | Won | -0.23 | 0.96 |
| 23-Sep-06 | vs Temple (116) | 41-7 | Won | -2.25 | 0.00 |
| 07-Oct-06 | at Ohio U. (60) | 20-27 | Lost | 0.13 | -0.68 |
| 14-Oct-06 | vs Northern Illinois (81) | 16-14 | Won | -0.81 | 0.39 |
| 21-Oct-06 | at Ball St (87) | 41-27 | Won | -0.57 | 0.63 |
| 28-Oct-06 | vs Eastern Michigan (111) | 18-15 | Won | -1.98 | 0.00 |
| 04-Nov-06 | vs Miami OH (109) | 27-24 | Won | -1.83 | 0.00 |
| 10-Nov-06 | at Central Michigan (55) | 7-31 | Lost | 0.21 | -0.59 |
| 18-Nov-06 | at Florida St (50) | 20-28 | Lost | 0.28 | -0.52 |
| 24-Nov-06 | at Akron (102) | 17-0 | Won | -0.94 | 0.25 |
A red opponent rating indicates modification according to home field advantage (0.24).