| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | vs Eastern Michigan (111) | 38-20 | Won | -1.98 | 0.00 |
| 09-Sep-06 | vs Indiana (48) | 23-24 | Lost | -0.12 | -0.31 |
| 16-Sep-06 | at Purdue (40) | 28-38 | Lost | 0.71 | 0.00 |
| 30-Sep-06 | vs Northern Illinois (81) | 28-40 | Lost | -0.81 | -1.00 |
| 07-Oct-06 | at Buffalo (115) | 55-25 | Won | -1.69 | 0.12 |
| 14-Oct-06 | at Central Michigan (55) | 7-18 | Lost | 0.21 | 0.00 |
| 21-Oct-06 | vs Western Michigan (64) | 27-41 | Lost | -0.44 | -0.63 |
| 28-Oct-06 | at Miami OH (109) | 20-17 | Won | -1.35 | 0.46 |
| 04-Nov-06 | at Michigan (2) | 26-34 | Lost | 3.27 | 0.00 |
| 14-Nov-06 | at Toledo (104) | 20-17 | Won | -0.99 | 0.82 |
| 24-Nov-06 | vs Kent St (98) | 30-6 | Won | -1.29 | 0.52 |
A red opponent rating indicates modification according to home field advantage (0.24).