| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 09-Sep-06 | at Northern Illinois (81) | 35-23 | Won | -0.33 | 0.79 |
| 16-Sep-06 | at Rutgers (22) | 7-24 | Lost | 1.35 | 0.00 |
| 23-Sep-06 | at Missouri (44) | 6-31 | Lost | 0.53 | -0.36 |
| 30-Sep-06 | vs Bowling Green (113) | 9-21 | Lost | -2.08 | -1.00 |
| 07-Oct-06 | vs Western Michigan (64) | 27-20 | Won | -0.44 | 0.68 |
| 14-Oct-06 | at Illinois (100) | 20-17 | Won | -0.86 | 0.25 |
| 21-Oct-06 | vs Buffalo (115) | 42-7 | Won | -2.17 | 0.00 |
| 28-Oct-06 | at Kent St (98) | 17-7 | Won | -0.81 | 0.31 |
| 04-Nov-06 | at Eastern Michigan (111) | 16-10 | Won | -1.50 | 0.00 |
| 16-Nov-06 | vs Akron (102) | 17-7 | Won | -1.43 | 0.00 |
| 24-Nov-06 | at Miami OH (109) | 34-24 | Won | -1.35 | 0.00 |
| 30-Nov-06 | at Central Michigan (55) | 10-31 | Lost | 0.21 | -0.67 |
A red opponent rating indicates modification according to home field advantage (0.24).