| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Wisconsin (6) | 14-35 | Lost | 1.99 | 0.00 |
| 09-Sep-06 | vs Buffalo (115) | 48-40 | Won | -2.17 | 0.67 |
| 16-Sep-06 | at Florida Int'l (119) | 33-28 | Won | -2.79 | 0.05 |
| 23-Sep-06 | vs Kent St (98) | 3-38 | Lost | -1.29 | -0.45 |
| 30-Sep-06 | at Ohio U. (60) | 21-9 | Won | 0.13 | 1.00 |
| 07-Oct-06 | at Ohio State (1) | 7-35 | Lost | 3.96 | 0.00 |
| 14-Oct-06 | vs Eastern Michigan (111) | 24-21 | Won | -1.98 | 0.86 |
| 19-Oct-06 | at Central Michigan (55) | 14-31 | Lost | 0.21 | 0.00 |
| 28-Oct-06 | at Temple (116) | 14-28 | Lost | -1.77 | -0.92 |
| 04-Nov-06 | at Akron (102) | 28-35 | Lost | -0.94 | -0.10 |
| 15-Nov-06 | vs Miami OH (109) | 7-9 | Lost | -1.83 | -0.99 |
| 21-Nov-06 | at Toledo (104) | 21-31 | Lost | -0.99 | -0.15 |
A red opponent rating indicates modification according to home field advantage (0.24).