| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | at Indiana (47) | 20-39 | Lost | 0.3773 | -0.4346 |
| 09-Sep-06 | vs Toledo (104) | 31-10 | Won | -1.4333 | -0.0000 |
| 16-Sep-06 | at Virginia (77) | 17-10 | Won | -0.2419 | 0.9462 |
| 23-Sep-06 | vs Temple (116) | 41-7 | Won | -2.1469 | -0.0000 |
| 07-Oct-06 | at Ohio U. (49) | 20-27 | Lost | 0.2740 | -0.5378 |
| 14-Oct-06 | vs Northern Illinois (81) | 16-14 | Won | -0.7402 | 0.4479 |
| 21-Oct-06 | at Ball St (89) | 41-27 | Won | -0.5655 | 0.6226 |
| 28-Oct-06 | vs Eastern Michigan (111) | 18-15 | Won | -1.8869 | -0.0000 |
| 04-Nov-06 | vs Miami OH (109) | 27-24 | Won | -1.7540 | -0.0000 |
| 10-Nov-06 | at Central Michigan (63) | 7-31 | Lost | 0.0371 | -0.7748 |
| 18-Nov-06 | at Florida St (51) | 20-28 | Lost | 0.2629 | -0.5490 |
| 24-Nov-06 | at Akron (102) | 17-0 | Won | -0.9147 | 0.2734 |
A red opponent rating indicates modification according to home field advantage (0.2218).