| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Western Michigan (64) | 39-20 | Won | -0.4100 | 0.4346 |
| 09-Sep-06 | at Ball St (89) | 24-23 | Won | -0.5655 | 0.2790 |
| 23-Sep-06 | vs Connecticut (69) | 7-14 | Lost | -0.4843 | -1.0000 |
| 30-Sep-06 | vs Wisconsin (6) | 17-52 | Lost | 1.9353 | 0.0000 |
| 07-Oct-06 | at Illinois (98) | 34-32 | Won | -0.7988 | 0.0458 |
| 14-Oct-06 | vs Iowa (48) | 31-28 | Won | -0.1152 | 0.7294 |
| 21-Oct-06 | at Ohio State (1) | 3-44 | Lost | 3.7926 | 0.0000 |
| 28-Oct-06 | vs Michigan St (71) | 46-21 | Won | -0.5119 | 0.3327 |
| 04-Nov-06 | at Minnesota (39) | 26-63 | Lost | 0.7653 | -0.3902 |
| 11-Nov-06 | vs Michigan (2) | 3-34 | Lost | 2.6837 | 0.0000 |
| 18-Nov-06 | at Purdue (40) | 19-28 | Lost | 0.7291 | -0.4263 |
A red opponent rating indicates modification according to home field advantage (0.2218).