| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | vs Eastern Michigan (111) | 38-20 | Won | -1.8869 | -0.0000 |
| 09-Sep-06 | vs Indiana (47) | 23-24 | Lost | -0.0664 | -0.2790 |
| 16-Sep-06 | at Purdue (40) | 28-38 | Lost | 0.7291 | 0.0000 |
| 30-Sep-06 | vs Northern Illinois (81) | 28-40 | Lost | -0.7402 | -0.9528 |
| 07-Oct-06 | at Buffalo (115) | 55-25 | Won | -1.6410 | 0.1464 |
| 14-Oct-06 | at Central Michigan (63) | 7-18 | Lost | 0.0371 | -0.1755 |
| 21-Oct-06 | vs Western Michigan (64) | 27-41 | Lost | -0.4100 | -0.6226 |
| 28-Oct-06 | at Miami OH (109) | 20-17 | Won | -1.3103 | 0.4770 |
| 04-Nov-06 | at Michigan (2) | 26-34 | Lost | 3.1274 | 0.0000 |
| 14-Nov-06 | at Toledo (104) | 20-17 | Won | -0.9897 | 0.7977 |
| 24-Nov-06 | vs Kent St (94) | 30-6 | Won | -1.2034 | 0.5840 |
A red opponent rating indicates modification according to home field advantage (0.2218).