| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | at Ball St (89) | 20-38 | Lost | -0.5655 | 0.0000 |
| 09-Sep-06 | at Michigan St (71) | 20-52 | Lost | -0.0682 | 0.0000 |
| 16-Sep-06 | at Northwestern (78) | 6-14 | Lost | -0.2735 | 0.0000 |
| 23-Sep-06 | vs Central Michigan (63) | 17-24 | Lost | -0.4065 | 0.0000 |
| 30-Sep-06 | at Louisiana-Lafayette (84) | 14-33 | Lost | -0.4189 | 0.0000 |
| 14-Oct-06 | at Bowling Green (112) | 21-24 | Lost | -1.5480 | -0.8829 |
| 21-Oct-06 | vs Toledo (104) | 17-13 | Won | -1.4333 | 1.0000 |
| 28-Oct-06 | at Western Michigan (64) | 15-18 | Lost | 0.0337 | 0.0000 |
| 04-Nov-06 | vs Ohio U. (49) | 10-16 | Lost | -0.1696 | 0.0000 |
| 11-Nov-06 | vs Navy (42) | 21-49 | Lost | 0.2335 | 0.0000 |
| 17-Nov-06 | at Kent St (94) | 6-14 | Lost | -0.7598 | -0.0947 |
| 24-Nov-06 | vs Northern Illinois (81) | 0-27 | Lost | -0.7402 | -0.0751 |
A red opponent rating indicates modification according to home field advantage (0.2218).