| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | at Miami OH (109) | 21-3 | Won | -1.3103 | 0.1850 |
| 16-Sep-06 | vs Eastern Michigan (111) | 14-6 | Won | -1.8869 | -0.0000 |
| 22-Sep-06 | at Nevada (50) | 21-31 | Lost | 0.2702 | -0.2345 |
| 30-Sep-06 | at Penn State (13) | 7-33 | Lost | 1.6986 | 0.0000 |
| 07-Oct-06 | at Wisconsin (6) | 9-41 | Lost | 2.3789 | 0.0000 |
| 14-Oct-06 | vs Purdue (40) | 10-31 | Lost | 0.2855 | -0.2192 |
| 21-Oct-06 | vs Michigan St (71) | 38-41 | Lost | -0.5119 | -1.0000 |
| 28-Oct-06 | at Michigan (2) | 3-17 | Lost | 3.1274 | 0.0000 |
| 04-Nov-06 | at Iowa (48) | 21-7 | Won | 0.3285 | 1.0000 |
| 11-Nov-06 | vs Ohio State (1) | 10-54 | Lost | 3.3490 | 0.0000 |
| 18-Nov-06 | vs Illinois (98) | 27-16 | Won | -1.2424 | 0.2530 |
A red opponent rating indicates modification according to home field advantage (0.2218).