| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Western Michigan (62) | 39-20 | Won | -0.2682 | 0.4800 |
| 09-Sep-06 | at Ball St (88) | 24-23 | Won | -0.3050 | 0.4432 |
| 23-Sep-06 | vs Connecticut (66) | 7-14 | Lost | -0.4120 | -1.0000 |
| 30-Sep-06 | vs Wisconsin (5) | 17-52 | Lost | 1.2333 | -0.0185 |
| 07-Oct-06 | at Illinois (101) | 34-32 | Won | -0.6345 | 0.1136 |
| 14-Oct-06 | vs Iowa (48) | 31-28 | Won | -0.0196 | 0.7286 |
| 21-Oct-06 | at Ohio State (1) | 3-44 | Lost | 2.4191 | 0.0000 |
| 28-Oct-06 | vs Michigan St (65) | 46-21 | Won | -0.3649 | 0.3832 |
| 04-Nov-06 | at Minnesota (32) | 26-63 | Lost | 0.7133 | -0.5385 |
| 11-Nov-06 | vs Michigan (2) | 3-34 | Lost | 1.7731 | 0.0000 |
| 18-Nov-06 | at Purdue (31) | 19-28 | Lost | 0.7400 | -0.5119 |
A red opponent rating indicates modification according to home field advantage (0.2077).