| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | vs Eastern Michigan (110) | 38-20 | Won | -1.2946 | 0.2180 |
| 09-Sep-06 | vs Indiana (44) | 23-24 | Lost | 0.0442 | -0.4432 |
| 16-Sep-06 | at Purdue (31) | 28-38 | Lost | 0.7400 | 0.0000 |
| 30-Sep-06 | vs Northern Illinois (71) | 28-40 | Lost | -0.5033 | -0.9906 |
| 07-Oct-06 | at Buffalo (113) | 55-25 | Won | -0.9960 | 0.5167 |
| 14-Oct-06 | at Central Michigan (58) | 7-18 | Lost | 0.2465 | -0.2408 |
| 21-Oct-06 | vs Western Michigan (62) | 27-41 | Lost | -0.2682 | -0.7555 |
| 28-Oct-06 | at Miami OH (109) | 20-17 | Won | -0.8532 | 0.6595 |
| 04-Nov-06 | at Michigan (2) | 26-34 | Lost | 2.1885 | 0.0000 |
| 14-Nov-06 | at Toledo (103) | 20-17 | Won | -0.6389 | 0.8738 |
A red opponent rating indicates modification according to home field advantage (0.2077).