| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | vs Northwestern (73) | 3-21 | Lost | -0.5109 | -0.4500 |
| 09-Sep-06 | at Purdue (31) | 31-38 | Lost | 0.7400 | 0.0000 |
| 16-Sep-06 | vs Kent St (79) | 14-16 | Lost | -0.6088 | -0.5479 |
| 23-Sep-06 | at Syracuse (69) | 14-34 | Lost | -0.0349 | 0.0000 |
| 30-Sep-06 | at Cincinnati (35) | 10-24 | Lost | 0.6104 | 0.0000 |
| 08-Oct-06 | vs Northern Illinois (71) | 25-28 | Lost | -0.5033 | -0.4424 |
| 15-Oct-06 | at Buffalo (113) | 38-31 | Won | -0.9960 | 1.0000 |
| 21-Oct-06 | at Akron (86) | 13-24 | Lost | -0.2967 | -0.2358 |
| 28-Oct-06 | vs Ball St (88) | 17-20 | Lost | -0.7204 | -0.6595 |
| 04-Nov-06 | at Western Michigan (62) | 24-27 | Lost | 0.1472 | 0.0000 |
| 15-Nov-06 | at Bowling Green (107) | 9-7 | Won | -0.8025 | 1.0000 |
A red opponent rating indicates modification according to home field advantage (0.2077).