| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | at Penn State (15) | 16-34 | Lost | 1.2471 | 0.0000 |
| 09-Sep-06 | at North Carolina St (96) | 20-17 | Won | -0.5019 | 1.0000 |
| 16-Sep-06 | at Central Michigan (58) | 21-24 | Lost | 0.2465 | -0.2491 |
| 23-Sep-06 | vs North Texas (111) | 33-13 | Won | -1.3048 | 0.1996 |
| 30-Sep-06 | at Kent St (79) | 15-37 | Lost | -0.1934 | -0.6890 |
| 07-Oct-06 | at Cincinnati (35) | 14-20 | Lost | 0.6104 | 0.0000 |
| 21-Oct-06 | vs Miami OH (109) | 24-13 | Won | -1.2686 | 0.2358 |
| 28-Oct-06 | at Toledo (103) | 20-35 | Lost | -0.6389 | -1.0000 |
| 04-Nov-06 | vs Bowling Green (107) | 35-28 | Won | -1.2179 | 0.2865 |
| 09-Nov-06 | vs Buffalo (113) | 31-16 | Won | -1.4114 | 0.0930 |
| 16-Nov-06 | at Ohio U. (45) | 7-17 | Lost | 0.4591 | -0.0364 |
A red opponent rating indicates modification according to home field advantage (0.2077).