| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Wisconsin (5) | 14-35 | Lost | 1.2333 | 0.0000 |
| 09-Sep-06 | vs Buffalo (113) | 48-40 | Won | -1.4114 | 0.5988 |
| 16-Sep-06 | at Florida Int'l (119) | 33-28 | Won | -1.8084 | 0.2018 |
| 23-Sep-06 | vs Kent St (79) | 3-38 | Lost | -0.6088 | -0.5986 |
| 30-Sep-06 | at Ohio U. (45) | 21-9 | Won | 0.4591 | 1.0000 |
| 07-Oct-06 | at Ohio State (1) | 7-35 | Lost | 2.4191 | 0.0000 |
| 14-Oct-06 | vs Eastern Michigan (110) | 24-21 | Won | -1.2946 | 0.7155 |
| 19-Oct-06 | at Central Michigan (58) | 14-31 | Lost | 0.2465 | 0.0000 |
| 28-Oct-06 | at Temple (112) | 14-28 | Lost | -0.9605 | -0.9503 |
| 04-Nov-06 | at Akron (86) | 28-35 | Lost | -0.2967 | -0.2865 |
| 15-Nov-06 | vs Miami OH (109) | 7-9 | Lost | -1.2686 | -1.0000 |
A red opponent rating indicates modification according to home field advantage (0.2077).