| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 09-Sep-06 | at Rutgers (3) | 0-33 | Lost | 1.8635 | 0.0000 |
| 16-Sep-06 | vs Syracuse (78) | 21-31 | Lost | -0.5928 | -0.8116 |
| 23-Sep-06 | vs Iowa (46) | 7-24 | Lost | 0.0381 | -0.1807 |
| 30-Sep-06 | at Michigan St (66) | 23-20 | Won | 0.0367 | 1.0000 |
| 07-Oct-06 | vs Indiana (40) | 32-34 | Lost | 0.1305 | -0.0883 |
| 14-Oct-06 | vs Ohio U. (44) | 17-20 | Lost | 0.0576 | -0.1612 |
| 21-Oct-06 | at Penn State (13) | 12-26 | Lost | 1.2382 | 0.0000 |
| 28-Oct-06 | at Wisconsin (6) | 24-30 | Lost | 1.6696 | 0.0000 |
| 04-Nov-06 | vs Ohio State (2) | 10-17 | Lost | 1.5521 | 0.0000 |
| 11-Nov-06 | vs Purdue (36) | 31-42 | Lost | 0.2136 | -0.0052 |
A red opponent rating indicates modification according to home field advantage (0.1961).