| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | at Wake Forest (16) | 10-20 | Lost | 1.2123 | 0.0000 |
| 09-Sep-06 | vs Iowa (46) | 13-20 | Lost | 0.0381 | -0.5652 |
| 16-Sep-06 | at Illinois (98) | 31-21 | Won | -0.5851 | 0.8116 |
| 23-Sep-06 | vs Miami OH (114) | 34-14 | Won | -1.5348 | -0.0000 |
| 30-Sep-06 | vs Wyoming (72) | 40-34 | Won | -0.5208 | 0.8759 |
| 07-Oct-06 | vs Pittsburgh (56) | 11-21 | Lost | -0.1350 | -0.7383 |
| 14-Oct-06 | at West Virginia (14) | 17-41 | Lost | 1.2372 | 0.0000 |
| 21-Oct-06 | vs Louisville (8) | 13-28 | Lost | 1.0679 | 0.0000 |
| 28-Oct-06 | at Cincinnati (52) | 3-17 | Lost | 0.3335 | -0.2698 |
| 11-Nov-06 | at South Florida (51) | 10-27 | Lost | 0.3636 | -0.2397 |
A red opponent rating indicates modification according to home field advantage (0.1961).