| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | vs Northwestern (82) | 3-21 | Lost | -0.6331 | -0.2943 |
| 09-Sep-06 | at Purdue (36) | 31-38 | Lost | 0.6058 | 0.0000 |
| 16-Sep-06 | vs Kent St (79) | 14-16 | Lost | -0.5997 | -0.2610 |
| 23-Sep-06 | at Syracuse (78) | 14-34 | Lost | -0.2006 | 0.0000 |
| 30-Sep-06 | at Cincinnati (52) | 10-24 | Lost | 0.3335 | 0.0000 |
| 08-Oct-06 | vs Northern Illinois (88) | 25-28 | Lost | -0.7055 | -0.3668 |
| 15-Oct-06 | at Buffalo (112) | 38-31 | Won | -1.0089 | 1.0000 |
| 21-Oct-06 | at Akron (84) | 13-24 | Lost | -0.2605 | 0.0000 |
| 28-Oct-06 | vs Ball St (92) | 17-20 | Lost | -0.8400 | -0.5013 |
| 04-Nov-06 | at Western Michigan (60) | 24-27 | Lost | 0.2295 | 0.0000 |
A red opponent rating indicates modification according to home field advantage (0.1961).