| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Western Michigan (60) | 39-20 | Won | -0.1627 | 0.5107 |
| 09-Sep-06 | at Ball St (92) | 24-23 | Won | -0.4479 | 0.2255 |
| 23-Sep-06 | vs Connecticut (58) | 7-14 | Lost | -0.1404 | -1.0000 |
| 30-Sep-06 | vs Wisconsin (6) | 17-52 | Lost | 1.2774 | -0.0492 |
| 07-Oct-06 | at Illinois (98) | 34-32 | Won | -0.5851 | 0.0883 |
| 14-Oct-06 | vs Iowa (46) | 31-28 | Won | 0.0381 | 0.7115 |
| 21-Oct-06 | at Ohio State (2) | 3-44 | Lost | 1.9443 | 0.0000 |
| 28-Oct-06 | vs Michigan St (66) | 46-21 | Won | -0.3555 | 0.3179 |
| 04-Nov-06 | at Minnesota (33) | 26-63 | Lost | 0.6252 | -0.7014 |
| 11-Nov-06 | vs Michigan (1) | 3-34 | Lost | 1.9931 | 0.0000 |
A red opponent rating indicates modification according to home field advantage (0.1961).