| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | at Kent St (78) | 44-0 | Won | -0.1835 | 0.6932 |
| 09-Sep-06 | at California (4) | 17-42 | Lost | 2.0145 | 0.0000 |
| 16-Sep-06 | vs Temple (112) | 62-0 | Won | -1.6401 | -0.0000 |
| 23-Sep-06 | at Purdue (45) | 21-27 | Lost | 0.5775 | -0.5457 |
| 30-Sep-06 | vs Michigan (1) | 14-28 | Lost | 2.3010 | 0.0000 |
| 07-Oct-06 | vs Penn State (16) | 27-28 | Lost | 0.9977 | -0.1256 |
| 14-Oct-06 | at Wisconsin (6) | 12-48 | Lost | 1.9393 | 0.0000 |
| 28-Oct-06 | at Ohio State (2) | 0-44 | Lost | 2.3530 | 0.0000 |
A red opponent rating indicates modification according to home field advantage (0.2405).