| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Akron (89) | 34-16 | Won | -0.9824 | -0.0000 |
| 09-Sep-06 | at Notre Dame (5) | 17-41 | Lost | 1.9935 | -0.2447 |
| 23-Sep-06 | at Ohio State (2) | 6-28 | Lost | 2.3530 | 0.0000 |
| 30-Sep-06 | vs Northwestern (86) | 33-7 | Won | -0.8793 | -0.0000 |
| 07-Oct-06 | at Minnesota (50) | 28-27 | Won | 0.3638 | 0.1256 |
| 14-Oct-06 | vs Michigan (1) | 10-17 | Lost | 2.3010 | 0.0000 |
| 21-Oct-06 | vs Illinois (83) | 26-12 | Won | -0.7798 | -0.0000 |
| 28-Oct-06 | at Purdue (45) | 12-0 | Won | 0.5775 | 0.3393 |
A red opponent rating indicates modification according to home field advantage (0.2405).