| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 14-Nov-05 | at Princeton (219) | 54-41 | Won | -0.0111 | 0.7517 |
| 17-Nov-05 | vs Sam Houston St (109) | 72-61 | Won | 0.0361 | 0.7989 |
| 21-Nov-05 | vs Rider (224) | 72-60 | Won | -0.7213 | 0.0415 |
| 23-Nov-05 | at Duke (1) | 68-78 | Lost | 2.0404 | 0.0000 |
| 25-Nov-05 | vs UCLA (7) | 56-57 | Lost | 1.6103 | 0.0000 |
| 26-Nov-05 | at Pennsylvania (121) | 60-68 | Lost | 0.6195 | -0.6178 |
| 29-Nov-05 | at St Joseph's PA (58) | 59-69 | Lost | 0.8236 | -0.4136 |
| 03-Dec-05 | vs La Salle (103) | 50-62 | Lost | 0.4625 | -0.7748 |
| 07-Dec-05 | vs James Madison (293) | 68-57 | Won | -1.2477 | -0.0000 |
| 10-Dec-05 | vs Old Dominion (56) | 61-42 | Won | 0.4859 | 1.0000 |
| 17-Dec-05 | at Fairleigh Dickinson (169) | 54-49 | Won | 0.3083 | 1.0000 |
| 20-Dec-05 | vs Ball St (209) | 56-51 | Won | -0.6597 | 0.1031 |
| 31-Dec-05 | at Monmouth NJ (181) | 53-49 | Won | 0.2327 | 0.9955 |
| 05-Jan-06 | at William & Mary (242) | 57-46 | Won | -0.1397 | 0.6230 |
| 07-Jan-06 | at VA Commonwealth (100) | 60-62 | Lost | 0.8320 | -0.4052 |
| 12-Jan-06 | vs UNC-Wilmington (34) | 60-66 | Lost | 0.7108 | -0.5265 |
| 14-Jan-06 | at Northeastern (95) | 60-63 | Lost | 0.8577 | -0.3795 |
| 19-Jan-06 | vs Georgia St (216) | 73-57 | Won | -0.6988 | 0.0639 |
| 21-Jan-06 | vs Delaware (236) | 55-44 | Won | -0.8056 | -0.0000 |
| 23-Jan-06 | vs Towson (186) | 69-61 | Won | -0.4865 | 0.2763 |
| 26-Jan-06 | at Old Dominion (56) | 67-74 | Lost | 1.1797 | -0.0576 |
| 28-Jan-06 | vs Hofstra (26) | 75-76 | Lost | 0.8357 | -0.4015 |
| 02-Feb-06 | at UNC-Wilmington (34) | 58-65 | Lost | 1.4045 | 0.0000 |
| 04-Feb-06 | at Towson (186) | 80-84 | Lost | 0.2073 | -1.0000 |
| 09-Feb-06 | vs Northeastern (95) | 83-47 | Won | 0.1640 | 0.9267 |
| 11-Feb-06 | at Delaware (236) | 68-75 | Lost | -0.1118 | -1.0000 |
| 15-Feb-06 | at George Mason (20) | 48-67 | Lost | 1.6296 | 0.0000 |
| 18-Feb-06 | vs Vermont (237) | 56-42 | Won | -0.8148 | -0.0000 |
| 23-Feb-06 | vs William & Mary (242) | 61-56 | Won | -0.8335 | -0.0000 |
| 25-Feb-06 | at Hofstra (26) | 68-70 | Lost | 1.5295 | 0.0000 |
| 03-Mar-06 | vs Delaware (236) | 49-52 | Lost | -0.4587 | -1.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).