| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | at Wake Forest (23) | 10-20 | Lost | 1.1685 | 0.0000 |
| 09-Sep-06 | vs Iowa (48) | 13-20 | Lost | -0.1152 | -0.8265 |
| 16-Sep-06 | at Illinois (98) | 31-21 | Won | -0.7988 | 0.4899 |
| 23-Sep-06 | vs Miami OH (109) | 34-14 | Won | -1.7540 | -0.0000 |
| 30-Sep-06 | vs Wyoming (73) | 40-34 | Won | -0.6314 | 0.6573 |
| 07-Oct-06 | vs Pittsburgh (59) | 11-21 | Lost | -0.2799 | -0.9912 |
| 14-Oct-06 | at West Virginia (28) | 17-41 | Lost | 1.0815 | 0.0000 |
| 21-Oct-06 | vs Louisville (16) | 13-28 | Lost | 1.0381 | 0.0000 |
| 28-Oct-06 | at Cincinnati (37) | 3-17 | Lost | 0.7802 | 0.0000 |
| 11-Nov-06 | at South Florida (44) | 10-27 | Lost | 0.5681 | -0.1432 |
| 18-Nov-06 | vs Connecticut (69) | 20-14 | Won | -0.4843 | 0.8044 |
| 25-Nov-06 | at Rutgers (14) | 7-38 | Lost | 1.6347 | 0.0000 |
A red opponent rating indicates modification according to home field advantage (0.2218).