| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | vs Northwestern (77) | 3-21 | Lost | -0.9466 | -0.1513 |
| 09-Sep-06 | at Purdue (35) | 31-38 | Lost | 0.9035 | 0.0000 |
| 16-Sep-06 | vs Kent St (86) | 14-16 | Lost | -1.1981 | -0.4027 |
| 23-Sep-06 | at Syracuse (78) | 14-34 | Lost | -0.3426 | 0.0000 |
| 30-Sep-06 | at Cincinnati (59) | 10-24 | Lost | 0.0436 | 0.0000 |
| 08-Oct-06 | vs Northern Illinois (67) | 25-28 | Lost | -0.7938 | 0.0000 |
| 15-Oct-06 | at Buffalo (112) | 38-31 | Won | -1.5385 | 1.0000 |
| 21-Oct-06 | at Akron (94) | 13-24 | Lost | -0.8051 | -0.0097 |
| 28-Oct-06 | vs Ball St (89) | 17-20 | Lost | -1.2885 | -0.4931 |
| 04-Nov-06 | at Western Michigan (47) | 24-27 | Lost | 0.3553 | 0.0000 |
A red opponent rating indicates modification according to home field advantage (0.3033).