| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 08-Sep-06 | vs Pittsburgh (49) | 15-33 | Lost | -0.3700 | -1.0000 |
| 16-Sep-06 | at Ohio State (2) | 7-37 | Lost | 3.6528 | 0.0000 |
| 23-Sep-06 | at Virginia Tech (34) | 13-29 | Lost | 0.9742 | 0.0000 |
| 30-Sep-06 | vs Miami OH (110) | 24-10 | Won | -2.0986 | -0.0000 |
| 07-Oct-06 | vs Akron (94) | 20-14 | Won | -1.4116 | -0.0000 |
| 14-Oct-06 | at Louisville (8) | 17-23 | Lost | 2.9293 | 0.0000 |
| 22-Oct-06 | vs South Florida (60) | 23-6 | Won | -0.5785 | 0.6812 |
| 28-Oct-06 | vs Syracuse (78) | 17-3 | Won | -0.9491 | 0.3106 |
A red opponent rating indicates modification according to home field advantage (0.3033).