| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 09-Sep-06 | at Rutgers (20) | 0-33 | Lost | 1.9509 | 0.0000 |
| 16-Sep-06 | vs Syracuse (78) | 21-31 | Lost | -0.9491 | -0.8906 |
| 23-Sep-06 | vs Iowa (46) | 7-24 | Lost | -0.1410 | -0.0825 |
| 30-Sep-06 | at Michigan St (52) | 23-20 | Won | 0.1801 | 1.0000 |
| 07-Oct-06 | vs Indiana (43) | 32-34 | Lost | -0.0608 | -0.0023 |
| 14-Oct-06 | vs Ohio U. (45) | 17-20 | Lost | -0.1165 | -0.0580 |
| 21-Oct-06 | at Penn State (18) | 12-26 | Lost | 2.0751 | 0.0000 |
| 28-Oct-06 | at Wisconsin (11) | 24-30 | Lost | 2.6962 | 0.0000 |
| 04-Nov-06 | vs Ohio State (2) | 10-17 | Lost | 3.0462 | 0.0000 |
A red opponent rating indicates modification according to home field advantage (0.3033).