| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Idaho (80) | 27-17 | Won | -0.9992 | 0.1240 |
| 09-Sep-06 | vs Eastern Michigan (104) | 52-20 | Won | -1.8060 | -0.0000 |
| 16-Sep-06 | at Pittsburgh (49) | 38-23 | Won | 0.2365 | 1.0000 |
| 23-Sep-06 | vs Notre Dame (10) | 37-40 | Lost | 2.2457 | 0.0000 |
| 30-Sep-06 | vs Illinois (91) | 20-23 | Lost | -1.3617 | -1.0000 |
| 07-Oct-06 | at Michigan (1) | 13-31 | Lost | 4.0374 | 0.0000 |
| 14-Oct-06 | vs Ohio State (2) | 7-38 | Lost | 3.0462 | 0.0000 |
| 21-Oct-06 | at Northwestern (77) | 41-38 | Won | -0.3401 | 0.7831 |
| 28-Oct-06 | at Indiana (43) | 21-46 | Lost | 0.5457 | -0.3311 |
| 04-Nov-06 | vs Purdue (35) | 15-17 | Lost | 0.2970 | -0.5798 |
A red opponent rating indicates modification according to home field advantage (0.3033).