| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | at Wake Forest (17) | 10-20 | Lost | 0.95 | 0.00 |
| 09-Sep-06 | vs Iowa (57) | 13-20 | Lost | -0.17 | -0.99 |
| 16-Sep-06 | at Illinois (108) | 31-21 | Won | -0.63 | 0.55 |
| 23-Sep-06 | vs Miami OH (109) | 34-14 | Won | -1.08 | 0.10 |
| 30-Sep-06 | vs Wyoming (68) | 40-34 | Won | -0.29 | 0.89 |
| 07-Oct-06 | vs Pittsburgh (58) | 11-21 | Lost | -0.17 | -0.99 |
| 14-Oct-06 | at West Virginia (10) | 17-41 | Lost | 1.09 | 0.00 |
| 21-Oct-06 | vs Louisville (7) | 13-28 | Lost | 0.87 | 0.00 |
| 28-Oct-06 | at Cincinnati (30) | 3-17 | Lost | 0.60 | -0.22 |
| 11-Nov-06 | at South Florida (34) | 10-27 | Lost | 0.56 | -0.26 |
| 18-Nov-06 | vs Connecticut (74) | 20-14 | Won | -0.43 | 0.75 |
| 25-Nov-06 | at Rutgers (11) | 7-38 | Lost | 1.08 | 0.00 |
A red opponent rating indicates modification according to home field advantage (0.19).