| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 19-Nov-05 | at Xavier OH (71) | 35-80 | Lost | 1.0213 | 0.0000 |
| 22-Nov-05 | at St Louis (106) | 45-69 | Lost | 0.4145 | 0.0000 |
| 29-Nov-05 | at Western Illinois (310) | 68-76 | Lost | -0.8867 | -0.8625 |
| 03-Dec-05 | vs Indiana St (136) | 58-66 | Lost | -0.1373 | -0.1131 |
| 08-Dec-05 | vs Tennessee Tech (150) | 80-83 | Lost | -0.2294 | -0.2052 |
| 12-Dec-05 | vs Tennessee St (202) | 68-84 | Lost | -0.5983 | -0.5741 |
| 19-Dec-05 | at Eastern Kentucky (193) | 50-57 | Lost | 0.1399 | 0.0000 |
| 21-Dec-05 | at Morehead St (323) | 57-56 | Won | -1.1139 | 0.9103 |
| 28-Dec-05 | at Missouri (144) | 56-68 | Lost | 0.4890 | 0.0000 |
| 30-Dec-05 | at UMKC (240) | 72-67 | Won | -0.1368 | 1.0000 |
| 05-Jan-06 | vs SE Missouri St (312) | 60-72 | Lost | -1.5933 | -1.0000 |
| 07-Jan-06 | at Austin Peay (175) | 56-62 | Lost | 0.2574 | 0.0000 |
| 09-Jan-06 | at Murray St (76) | 65-66 | Lost | 0.9907 | 0.0000 |
| 12-Jan-06 | vs Tennessee-Martin (207) | 80-70 | Won | -0.6543 | 1.0000 |
| 14-Jan-06 | vs Eastern Kentucky (193) | 46-71 | Lost | -0.5539 | -0.5297 |
| 16-Jan-06 | vs Murray St (76) | 59-54 | Won | 0.2969 | 1.0000 |
| 19-Jan-06 | at Tennessee Tech (150) | 60-75 | Lost | 0.4644 | 0.0000 |
| 21-Jan-06 | at Tennessee St (202) | 57-73 | Lost | 0.0955 | 0.0000 |
| 28-Jan-06 | vs Morehead St (323) | 80-65 | Won | -1.8077 | 0.2165 |
| 02-Feb-06 | at Jacksonville St (183) | 51-66 | Lost | 0.2212 | 0.0000 |
| 04-Feb-06 | at Samford (113) | 55-58 | Lost | 0.7131 | 0.0000 |
| 09-Feb-06 | vs Austin Peay (175) | 61-70 | Lost | -0.4364 | -0.4122 |
| 11-Feb-06 | at Tennessee-Martin (207) | 61-85 | Lost | 0.0394 | 0.0000 |
| 15-Feb-06 | at SE Missouri St (312) | 60-49 | Won | -0.8995 | 1.0000 |
| 18-Feb-06 | vs Eastern Michigan (276) | 50-65 | Lost | -1.0788 | -1.0000 |
| 23-Feb-06 | vs Jacksonville St (183) | 68-75 | Lost | -0.4726 | -0.4484 |
| 25-Feb-06 | vs Samford (113) | 41-52 | Lost | 0.0193 | 0.0000 |
A red opponent rating indicates modification according to home court advantage (0.3469).