| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Virginia (76) | 38-13 | Won | -0.72 | 0.35 |
| 08-Sep-06 | at Cincinnati (34) | 33-15 | Won | 0.82 | 1.00 |
| 16-Sep-06 | vs Michigan St (72) | 23-38 | Lost | -0.59 | -1.00 |
| 30-Sep-06 | vs Toledo (104) | 45-3 | Won | -1.48 | 0.00 |
| 07-Oct-06 | at Syracuse (70) | 21-11 | Won | -0.09 | 0.98 |
| 13-Oct-06 | at Central Florida (95) | 52-7 | Won | -0.79 | 0.28 |
| 21-Oct-06 | vs Rutgers (22) | 10-20 | Lost | 0.87 | -0.07 |
| 04-Nov-06 | at South Florida (45) | 12-22 | Lost | 0.52 | -0.41 |
| 11-Nov-06 | at Connecticut (68) | 45-46 | Lost | -0.04 | -0.97 |
| 16-Nov-06 | vs West Virginia (25) | 27-45 | Lost | 0.77 | -0.16 |
| 25-Nov-06 | vs Louisville (18) | 24-48 | Lost | 0.98 | 0.00 |
A red opponent rating indicates modification according to home field advantage (0.24).