| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Wisconsin (11) | 14-35 | Lost | 2.0896 | 0.0000 |
| 09-Sep-06 | vs Buffalo (112) | 48-40 | Won | -2.1450 | 0.3109 |
| 16-Sep-06 | at Florida Int'l (119) | 33-28 | Won | -2.3713 | 0.0846 |
| 23-Sep-06 | vs Kent St (86) | 3-38 | Lost | -1.1981 | -0.7421 |
| 30-Sep-06 | at Ohio U. (45) | 21-9 | Won | 0.4900 | 1.0000 |
| 07-Oct-06 | at Ohio State (2) | 7-35 | Lost | 3.6528 | 0.0000 |
| 14-Oct-06 | vs Eastern Michigan (104) | 24-21 | Won | -1.8060 | 0.6499 |
| 19-Oct-06 | at Central Michigan (57) | 14-31 | Lost | 0.0707 | 0.0000 |
| 28-Oct-06 | at Temple (111) | 14-28 | Lost | -1.5360 | -1.0000 |
| 04-Nov-06 | at Akron (94) | 28-35 | Lost | -0.8051 | -0.3492 |
A red opponent rating indicates modification according to home field advantage (0.3033).