| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 08-Sep-06 | vs Pittsburgh (37) | 15-33 | Lost | 0.3180 | -0.7394 |
| 16-Sep-06 | at Ohio State (2) | 7-37 | Lost | 2.3530 | 0.0000 |
| 23-Sep-06 | at Virginia Tech (33) | 13-29 | Lost | 0.8963 | -0.1611 |
| 30-Sep-06 | vs Miami OH (113) | 24-10 | Won | -1.6619 | -0.0000 |
| 07-Oct-06 | vs Akron (89) | 20-14 | Won | -0.9824 | -0.0000 |
| 14-Oct-06 | at Louisville (13) | 17-23 | Lost | 1.6386 | 0.0000 |
| 22-Oct-06 | vs South Florida (71) | 23-6 | Won | -0.5566 | 0.3860 |
| 28-Oct-06 | vs Syracuse (64) | 17-3 | Won | -0.4179 | 0.5247 |
A red opponent rating indicates modification according to home field advantage (0.2405).