| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 10-Sep-05 | vs Wake Forest (58) | 31-3 | Won | -0.0709 | 0.3205 |
| 17-Sep-05 | vs Pittsburgh (63) | 7-6 | Won | -0.1944 | 0.1970 |
| 01-Oct-05 | vs Iowa St (39) | 27-20 | Won | 0.3183 | 0.7097 |
| 08-Oct-05 | vs Texas Tech (16) | 31-34 | Lost | 1.1641 | -0.4445 |
| 15-Oct-05 | at Baylor (52) | 23-14 | Won | 0.2784 | 0.6698 |
| 22-Oct-05 | at Missouri (44) | 24-41 | Lost | 0.4480 | -1.0000 |
| 29-Oct-05 | vs Oklahoma (24) | 24-31 | Lost | 0.8182 | -0.7904 |
| 05-Nov-05 | at Kansas (38) | 15-40 | Lost | 0.6617 | -0.9469 |
| 12-Nov-05 | vs Kansas St (59) | 27-25 | Won | -0.0728 | 0.3186 |
| 25-Nov-05 | at Colorado (32) | 30-3 | Won | 0.8578 | 1.0000 |
A red opponent rating indicates modification according to home field advantage (0.1322).